A cell penetrating peptide derived from azurin inhibits angiogenesis and tumor growth by inhibiting phosphorylation of VEGFR-2, FAK and Akt. R.R. Mehta, T. Yamada, B.N. Taylor, K. Christov, M.L. King, D. Dibyen Majumdar, F. Lekmine, C. Tiruppathi, A. Shilkaitis, L. Bratescu, A. Green, C.W. Beattie and T.K. Das Gupta.Angiogenesis. (2011)14(3):355-69.
Interaction of an anticancer peptide fragment of azurin with p53 and its isolated domains studied by atomic force spectroscopy. A.R. Bizzarri, S. Santini, E. Coppari, M. Bucciantini, S. Di Agostino, T. Yamada, C.W. Beattie, S. Cannistraro.Int J Nanomedicine. (2011) 6:3011-9.
Preclinical pharmacokinetics, metabolism, and toxicity of azurin-p28 (NSC745104) a peptide inhibitor of p53 ubiquitination L. Jia, G.S. Gorman, L.U. Coward, P.E. Noker, D. McCormick, T.L. Horn, J.B. Harder, M. Muzzio, B. Prabhakar, B. Ganesh, T.K. Das Gupta, C.W. Beattie. Cancer Chemother Pharmacol. (2010, November 18) [Epub ahead of print]
A novel and rapid LC/MS/MS assay for bioanalysis of Azurin p28 in serum and its pharmacokinetics in mice R.R. Mehta, M. Hawthorne, X. Peng, A. Shilkaitis, R.G. Mehta, C.W. Beattie, T.K. Das Gupta, G.S. Gorman, L.U. Coward, L. Freeman, P.E. Noker, C.W. Beattie, L. Jia. J Pharm Biomed Anal. (2010) 53(4):991-6.
A peptide fragment of azurin induces a p53-mediated cell cycle arrest in human breast cancer cells T. Yamada, R.R. Mehta, F. Lekmine, K. Christov, M.L. King, D. Majumdar, A. Shilkaitis, A. Green, L. Bratescu, C.W. Beattie, T.K. Das Gupta. Mol Cancer Ther. (2009) 8(10):2947-58.
Noncationic peptides obtained from azurin preferentially enter cancer cells B.N. Taylor, R.R. Mehta, T. Yamada, F. Lekmine, K. Christov, A.M. Chakrabarty, A. Green, L. Bratescu, A. Shilkaitis, C.W. Beattie, T.K. Das Gupta. Cancer Res. (2009) 69(2):537-46.
Azurin, Plasmodium falciparum malaria and HIV/AIDS: inhibition of parasitic and viral growth by Azurin A. Chaudhari, A.M. Fialho, D. Ratner, P. Gupta, C.S. Hong, S. Kahali, T. Yamada, K. Haldar, S. Murphy, W. Cho, V.S. Chauhan, T.K. Das Gupta, A.M. Chakrabarty. Cell Cycle. (2006) 5(15):1642-8.